It is advisable to use irrigation solutions which have strong antibacterial effect and weak cytotoxic effect on treating root infections. Streptococci are ones of the most frequently isolated microorganisms in infected root canals The
antibacterial
effect of ten irrigation solutions were investigated on S. mutans (19449), S. sanguis.)10556) and 4 streptococci isolated from saliva of healthy persons. These streptococci were exposured to irrigation solution during 10 sec, 30 sec, 1 min, 3
min,
5
min, 10 min, 30 min and 2hrs respectively. Four irrigation solutions which showed strong antibacterial activity were diluted to 1 : 1 to 1 : 10,000. Then they were subcultured on blood agar plate an observed after 1 day. 5.25% NaOC1 had the
strongest
antibacterial effect. 30% urea and normal saline showed no antibacterial effect. 50% citric acid and 3% H2O2 showed relatively weak antibacterial effect. 15% EDTA had very weak antibacterial effect.
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